{"symbol":"C5AR2","synonyms":["GPR77","GPF77","C5L2"],"name":"complement component 5a receptor 2","description":"This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]","ncbiEntrezGeneId":27202,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27202","proteins":[{"symbol":"C5AR2_HUMAN","href":"/api/1.0/protein/C5AR2_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}