{"symbol":"CACNA1G","synonyms":["CAV3.1","SCA42","SCA42ND","NBR13","CA(V)T.1"],"name":"calcium channel, voltage-dependent, T type, alpha 1G subunit","description":"Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]","ncbiEntrezGeneId":8913,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8913","proteins":[{"symbol":"CAC1G_HUMAN","href":"/api/1.0/protein/CAC1G_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}