{"symbol":"CACNA2D4","synonyms":["RCD4"],"name":"calcium channel, voltage-dependent, alpha 2/delta subunit 4","description":"This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":93589,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/93589","proteins":[{"symbol":"CA2D4_HUMAN","href":"/api/1.0/protein/CA2D4_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}