{"symbol":"CACNB1","synonyms":["CAB1","CCHLB1","CACNLB1"],"name":"calcium channel, voltage-dependent, beta 1 subunit","description":"The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":782,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/782","proteins":[{"symbol":"CACB1_HUMAN","href":"/api/1.0/protein/CACB1_HUMAN"}],"hgncRootFamilies":[{"name":"Membrane-associated guanylate kinases","href":"/api/1.0/gene_family/Membrane-associated+guanylate+kinases"},{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}