{"symbol":"CACNB2","synonyms":["CAVB2","MYSB","CACNLB2"],"name":"calcium channel, voltage-dependent, beta 2 subunit","description":"This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]","ncbiEntrezGeneId":783,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/783","proteins":[{"symbol":"CACB2_HUMAN","href":"/api/1.0/protein/CACB2_HUMAN"}],"hgncRootFamilies":[{"name":"Membrane-associated guanylate kinases","href":"/api/1.0/gene_family/Membrane-associated+guanylate+kinases"},{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}