{"symbol":"CALB2","synonyms":["CAB29","CAL2","CR"],"name":"calbindin 2","description":"This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]","ncbiEntrezGeneId":794,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/794","proteins":[{"symbol":"CALB2_HUMAN","href":"/api/1.0/protein/CALB2_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}