{"symbol":"CALM1","synonyms":["PHKD","CAMB","CAMI","CAMIII","CAMC","caM","LQT14","CALML2","CPVT4","CAM3","DD132"],"name":"calmodulin 1 (phosphorylase kinase, delta)","description":"This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.[provided by RefSeq, May 2020]","ncbiEntrezGeneId":801,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/801","proteins":[{"symbol":"CALM_HUMAN","href":"/api/1.0/protein/CALM_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"},{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"}]}