{"symbol":"CAMK2B","synonyms":["MRD54","CAMK2","CAM2","CAMKB"],"name":"calcium/calmodulin-dependent protein kinase II beta","description":"The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]","ncbiEntrezGeneId":816,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/816","proteins":[{"symbol":"KCC2B_HUMAN","href":"/api/1.0/protein/KCC2B_HUMAN"}],"hgncRootFamilies":[]}