{"symbol":"CAPN1","synonyms":["CANP","CANP1","CANPL1","SPG76","MUCANP","MUCL"],"name":"calpain 1, (mu/I) large subunit","description":"The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]","ncbiEntrezGeneId":823,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/823","proteins":[{"symbol":"CAN1_HUMAN","href":"/api/1.0/protein/CAN1_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}