{"symbol":"CARD10","synonyms":["CARMA3","BIMP1"],"name":"caspase recruitment domain family, member 10","description":"The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":29775,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/29775","proteins":[{"symbol":"CAR10_HUMAN","href":"/api/1.0/protein/CAR10_HUMAN"}],"hgncRootFamilies":[{"name":"Membrane-associated guanylate kinases","href":"/api/1.0/gene_family/Membrane-associated+guanylate+kinases"}]}