{"symbol":"CASP8AP2","synonyms":["FLASH","CED-4","RIP25"],"name":"caspase 8 associated protein 2","description":"This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]","ncbiEntrezGeneId":9994,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9994","proteins":[{"symbol":"C8AP2_HUMAN","href":"/api/1.0/protein/C8AP2_HUMAN"}],"hgncRootFamilies":[]}