{"symbol":"CBY1","synonyms":["C22ORF2","PIGEA14","PGEA1","HS508I15A","PIGEA-14","Chibby1","CBY"],"name":"chibby homolog 1 (Drosophila)","description":"Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":25776,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/25776","proteins":[{"symbol":"CBY1_HUMAN","href":"/api/1.0/protein/CBY1_HUMAN"}],"hgncRootFamilies":[]}