{"symbol":"CCDC8","synonyms":["PPP1R20","3M3"],"name":"coiled-coil domain containing 8","description":"This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011]","ncbiEntrezGeneId":83987,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/83987","proteins":[{"symbol":"CCDC8_HUMAN","href":"/api/1.0/protein/CCDC8_HUMAN"}],"hgncRootFamilies":[{"name":"Protein phosphatase 1 regulatory subunits (PPP1R)","href":"/api/1.0/gene_family/Protein+phosphatase+1+regulatory+subunits+%28PPP1R%29"}]}