{"symbol":"CCHCR1","synonyms":["C6ORF18","pg8"],"name":"coiled-coil alpha-helical rod protein 1","description":"This gene encodes a protein with five coiled-coil alpha-helical rod domains that is thought to act as a regulator of mRNA metabolism through its interaction with mRNA-decapping protein 4. It localizes to P-bodies, the site of mRNA metabolism, with an N-terminus that is required for this subcellular localization, suggesting it is a P-body component. Naturally occurring mutations in this gene are associated with psoriasis. [provided by RefSeq, May 2017]","ncbiEntrezGeneId":54535,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54535","proteins":[{"symbol":"CCHCR_HUMAN","href":"/api/1.0/protein/CCHCR_HUMAN"}],"hgncRootFamilies":[]}