{"symbol":"CCL1","synonyms":["TCA3","P500","SISE","SCYA1","I-309"],"name":"chemokine (C-C motif) ligand 1","description":"This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014]","ncbiEntrezGeneId":6346,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6346","proteins":[{"symbol":"CCL1_HUMAN","href":"/api/1.0/protein/CCL1_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"},{"name":"Chemokine ligands (CCL)","href":"/api/1.0/gene_family/Chemokine+ligands+%28CCL%29"}]}