{"symbol":"CCL11","synonyms":["SCYA11"],"name":"chemokine (C-C motif) ligand 11","description":"This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]","ncbiEntrezGeneId":6356,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6356","proteins":[{"symbol":"CCL11_HUMAN","href":"/api/1.0/protein/CCL11_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"},{"name":"Chemokine ligands (CCL)","href":"/api/1.0/gene_family/Chemokine+ligands+%28CCL%29"}]}