{"symbol":"CCL17","synonyms":["SCYA17","TARC","ABCD-2","A-152E5.3"],"name":"chemokine (C-C motif) ligand 17","description":"This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]","ncbiEntrezGeneId":6361,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6361","proteins":[{"symbol":"CCL17_HUMAN","href":"/api/1.0/protein/CCL17_HUMAN"}],"hgncRootFamilies":[{"name":"Chemokine ligands (CCL)","href":"/api/1.0/gene_family/Chemokine+ligands+%28CCL%29"},{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"}]}