{"symbol":"CCL27","synonyms":["PESKY","CTACK","ESKINE","ILC","CTAK","SCYA27"],"name":"chemokine (C-C motif) ligand 27","description":"This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]","ncbiEntrezGeneId":10850,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10850","proteins":[{"symbol":"CCL27_HUMAN","href":"/api/1.0/protein/CCL27_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"},{"name":"Chemokine ligands (CCL)","href":"/api/1.0/gene_family/Chemokine+ligands+%28CCL%29"}]}