{"symbol":"CCNB2","synonyms":["HST17299"],"name":"cyclin B2","description":"Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":9133,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9133","proteins":[{"symbol":"CCNB2_HUMAN","href":"/api/1.0/protein/CCNB2_HUMAN"}],"hgncRootFamilies":[{"name":"Cyclins (CCN)","href":"/api/1.0/gene_family/Cyclins+%28CCN%29"}]}