{"symbol":"CCNG2","synonyms":[],"name":"cyclin G2","description":"The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":901,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/901","proteins":[{"symbol":"CCNG2_HUMAN","href":"/api/1.0/protein/CCNG2_HUMAN"}],"hgncRootFamilies":[{"name":"Cyclins (CCN)","href":"/api/1.0/gene_family/Cyclins+%28CCN%29"}]}