{"symbol":"CCR6","synonyms":["GPR29","CKRL3","DCR2","CCR-6","GPRCY4","CD196","CKR-L3","CMKBR6","BN-1","DRY6","CC-CKR-6","C-C CKR-6","STRL22"],"name":"chemokine (C-C motif) receptor 6","description":"This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":1235,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1235","proteins":[{"symbol":"CCR6_HUMAN","href":"/api/1.0/protein/CCR6_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}