{"symbol":"CCT4","synonyms":["CCTD","SRB","CCT-DELTA"],"name":"chaperonin containing TCP1, subunit 4 (delta)","description":"The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":10575,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10575","proteins":[{"symbol":"TCPD_HUMAN","href":"/api/1.0/protein/TCPD_HUMAN"}],"hgncRootFamilies":[{"name":"Heat shock proteins","href":"/api/1.0/gene_family/Heat+shock+proteins"}]}