{"symbol":"CD151","synonyms":["MER2","RAPH","GP27","SFA1","TSPAN24","PETA-3"],"name":"CD151 molecule (Raph blood group)","description":"The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":977,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/977","proteins":[{"symbol":"CD151_HUMAN","href":"/api/1.0/protein/CD151_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Blood group antigens","href":"/api/1.0/gene_family/Blood+group+antigens"},{"name":"Tetraspanins (TSPAN)","href":"/api/1.0/gene_family/Tetraspanins+%28TSPAN%29"}]}