{"symbol":"CD180","synonyms":["LY64","RP105","LY78"],"name":"CD180 molecule","description":"CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":4064,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4064","proteins":[{"symbol":"CD180_HUMAN","href":"/api/1.0/protein/CD180_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}