{"symbol":"CD22","synonyms":["SIGLEC-2","SIGLEC2"],"name":"CD22 molecule","description":"Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. Implicated in diffuse large B-cell lymphoma. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":933,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/933","proteins":[{"symbol":"CD22_HUMAN","href":"/api/1.0/protein/CD22_HUMAN"}],"hgncRootFamilies":[{"name":"Sialic acid binding Ig-like lectins (SIGLECs)","href":"/api/1.0/gene_family/Sialic+acid+binding+Ig-like+lectins+%28SIGLECs%29"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}