{"symbol":"CD226","synonyms":["DNAM1","TLISA1","DNAM-1","PTA1"],"name":"CD226 molecule","description":"This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]","ncbiEntrezGeneId":10666,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10666","proteins":[{"symbol":"CD226_HUMAN","href":"/api/1.0/protein/CD226_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}