{"symbol":"CD33","synonyms":["SIGLEC-3","SIGLEC3","p67"],"name":"CD33 molecule","description":"Enables protein phosphatase binding activity; protein tyrosine phosphatase activator activity; and sialic acid binding activity. Involved in several processes, including immune response-regulating signaling pathway; negative regulation of cytokine production; and negative regulation of monocyte activation. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":945,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/945","proteins":[{"symbol":"CD33_HUMAN","href":"/api/1.0/protein/CD33_HUMAN"}],"hgncRootFamilies":[{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Sialic acid binding Ig-like lectins (SIGLECs)","href":"/api/1.0/gene_family/Sialic+acid+binding+Ig-like+lectins+%28SIGLECs%29"}]}