{"symbol":"CD37","synonyms":["TSPAN26","GP52-40"],"name":"CD37 molecule","description":"The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":951,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/951","proteins":[{"symbol":"CD37_HUMAN","href":"/api/1.0/protein/CD37_HUMAN"}],"hgncRootFamilies":[{"name":"Tetraspanins (TSPAN)","href":"/api/1.0/gene_family/Tetraspanins+%28TSPAN%29"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}