{"symbol":"CD3G","synonyms":["IMD17","CD3-GAMMA","T3G"],"name":"CD3g molecule, gamma (CD3-TCR complex)","description":"The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":917,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/917","proteins":[{"symbol":"CD3G_HUMAN","href":"/api/1.0/protein/CD3G_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}