{"symbol":"CD40LG","synonyms":["CD154","gp39","CD40L","IMD3","HIGM1","HCD40L","TNFSF5","IGM","T-BAM"],"name":"CD40 ligand","description":"The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":959,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/959","proteins":[{"symbol":"CD40L_HUMAN","href":"/api/1.0/protein/CD40L_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Tumor necrosis factor (ligand) superfamily (TNFSF)","href":"/api/1.0/gene_family/Tumor+necrosis+factor+%28ligand%29+superfamily+%28TNFSF%29"}]}