{"symbol":"CD70","synonyms":["TNLG8A","CD27LG","TNFSF7","CD27L","CD27-L"],"name":"CD70 molecule","description":"The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":970,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/970","proteins":[{"symbol":"CD70_HUMAN","href":"/api/1.0/protein/CD70_HUMAN"}],"hgncRootFamilies":[{"name":"Tumor necrosis factor (ligand) superfamily (TNFSF)","href":"/api/1.0/gene_family/Tumor+necrosis+factor+%28ligand%29+superfamily+%28TNFSF%29"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}