{"symbol":"CD80","synonyms":["LAB7","B7.1","B7","B7-1","CD28LG1","CD28LG"],"name":"CD80 molecule","description":"The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]","ncbiEntrezGeneId":941,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/941","proteins":[{"symbol":"CD80_HUMAN","href":"/api/1.0/protein/CD80_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}