{"symbol":"CDC40","synonyms":["PRPF17","EHB3","PRP17"],"name":"cell division cycle 40","description":"Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":51362,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51362","proteins":[{"symbol":"PRP17_HUMAN","href":"/api/1.0/protein/PRP17_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}