{"symbol":"CDC42BPA","synonyms":["MRCKA","PK428","MRCK"],"name":"CDC42 binding protein kinase alpha (DMPK-like)","description":"The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018]","ncbiEntrezGeneId":8476,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8476","proteins":[{"symbol":"MRCKA_HUMAN","href":"/api/1.0/protein/MRCKA_HUMAN"}],"hgncRootFamilies":[]}