{"symbol":"CDC42EP2","synonyms":["CEP2","BORG1"],"name":"CDC42 effector protein (Rho GTPase binding) 2","description":"CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011]","ncbiEntrezGeneId":10435,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10435","proteins":[{"symbol":"BORG1_HUMAN","href":"/api/1.0/protein/BORG1_HUMAN"}],"hgncRootFamilies":[]}