{"symbol":"CDC73","synonyms":["C1ORF28","HRPT2","HPTJT","HRPT1","HYX","FIHP"],"name":"cell division cycle 73","description":"This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3\u0027 mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]","ncbiEntrezGeneId":79577,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79577","proteins":[{"symbol":"CDC73_HUMAN","href":"/api/1.0/protein/CDC73_HUMAN"}],"hgncRootFamilies":[]}