{"symbol":"CDH17","synonyms":["HPT-1","CDH16","HPT1"],"name":"cadherin 17, LI cadherin (liver-intestine)","description":"This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]","ncbiEntrezGeneId":1015,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1015","proteins":[{"symbol":"CAD17_HUMAN","href":"/api/1.0/protein/CAD17_HUMAN"}],"hgncRootFamilies":[{"name":"Cadherins","href":"/api/1.0/gene_family/Cadherins"}]}