{"symbol":"CDKL5","synonyms":["ISSX","EIEE2","CFAP247","STK9"],"name":"cyclin-dependent kinase-like 5","description":"This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":6792,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6792","proteins":[{"symbol":"CDKL5_HUMAN","href":"/api/1.0/protein/CDKL5_HUMAN"}],"hgncRootFamilies":[{"name":"Cyclin-dependent kinases (CDK)","href":"/api/1.0/gene_family/Cyclin-dependent+kinases+%28CDK%29"}]}