{"symbol":"CELF1","synonyms":["BRUNOL2","CUG-BP","CUGBP1","CUGBP","NAB50","HNAB50","NAPOR","EDEN-BP"],"name":"CUGBP, Elav-like family member 1","description":"Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10658,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10658","proteins":[{"symbol":"CELF1_HUMAN","href":"/api/1.0/protein/CELF1_HUMAN"}],"hgncRootFamilies":[{"name":"RNA binding motif containing (RBM)","href":"/api/1.0/gene_family/RNA+binding+motif+containing+%28RBM%29"}]}