{"symbol":"CERKL","synonyms":["RP26"],"name":"ceramide kinase-like","description":"This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010]","ncbiEntrezGeneId":375298,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/375298","proteins":[{"symbol":"CERKL_HUMAN","href":"/api/1.0/protein/CERKL_HUMAN"}],"hgncRootFamilies":[]}