{"symbol":"CFHR3","synonyms":["FHR-3","HLF4","FHR3","DOWN16"],"name":"complement factor H-related 3","description":"The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]","ncbiEntrezGeneId":10878,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10878","proteins":[{"symbol":"FHR3_HUMAN","href":"/api/1.0/protein/FHR3_HUMAN"}],"hgncRootFamilies":[{"name":"Complement system","href":"/api/1.0/gene_family/Complement+system"}]}