{"symbol":"CHSY1","synonyms":["CHSY-1","TPBS","CHSY"],"name":"chondroitin sulfate synthase 1","description":"This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome. [provided by RefSeq, Dec 2011]","ncbiEntrezGeneId":22856,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/22856","proteins":[{"symbol":"CHSS1_HUMAN","href":"/api/1.0/protein/CHSS1_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}