{"symbol":"CHUK","synonyms":["IKK1","IKBKA","TCF16","IKK-ALPHA","NFKBIKA","IKKA"],"name":"conserved helix-loop-helix ubiquitous kinase","description":"This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":1147,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1147","proteins":[{"symbol":"IKKA_HUMAN","href":"/api/1.0/protein/IKKA_HUMAN"}],"hgncRootFamilies":[]}