{"symbol":"CLCA1","synonyms":["CACC1","HCLCA1","CLCRG1","HCACC-1","CACC","CACC-1","GOB5"],"name":"chloride channel accessory 1","description":"This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":1179,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1179","proteins":[{"symbol":"CLCA1_HUMAN","href":"/api/1.0/protein/CLCA1_HUMAN"}],"hgncRootFamilies":[{"name":"Chloride channel accessory (CLCA)","href":"/api/1.0/gene_family/Chloride+channel+accessory+%28CLCA%29"}]}