{"symbol":"CLEC4E","synonyms":["CLECSF9","MINCLE"],"name":"C-type lectin domain family 4, member E","description":"This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":26253,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/26253","proteins":[{"symbol":"CLC4E_HUMAN","href":"/api/1.0/protein/CLC4E_HUMAN"}],"hgncRootFamilies":[{"name":"C-type lectin domain family (CLEC)","href":"/api/1.0/gene_family/C-type+lectin+domain+family+%28CLEC%29"}]}