{"symbol":"CLIC2","synonyms":["XAP121","MRXS32","CLIC2B"],"name":"chloride intracellular channel 2","description":"This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein plays a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]","ncbiEntrezGeneId":1193,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1193","proteins":[{"symbol":"CLIC2_HUMAN","href":"/api/1.0/protein/CLIC2_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}