{"symbol":"CLK1","synonyms":["CLK/STY","CLK","STY"],"name":"CDC-like kinase 1","description":"This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]","ncbiEntrezGeneId":1195,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1195","proteins":[{"symbol":"CLK1_HUMAN","href":"/api/1.0/protein/CLK1_HUMAN"}],"hgncRootFamilies":[{"name":"CDC-like kinases (CLK)","href":"/api/1.0/gene_family/CDC-like+kinases+%28CLK%29"}]}