{"symbol":"CLNK","synonyms":["MIST"],"name":"cytokine-dependent hematopoietic cell linker","description":"MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":116449,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/116449","proteins":[{"symbol":"CLNK_HUMAN","href":"/api/1.0/protein/CLNK_HUMAN"}],"hgncRootFamilies":[{"name":"SH2 domain containing","href":"/api/1.0/gene_family/SH2+domain+containing"}]}