{"symbol":"CLSPN","synonyms":[],"name":"claspin","description":"The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]","ncbiEntrezGeneId":63967,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/63967","proteins":[{"symbol":"CLSPN_HUMAN","href":"/api/1.0/protein/CLSPN_HUMAN"}],"hgncRootFamilies":[]}