{"symbol":"CMBL","synonyms":["JS-1"],"name":"carboxymethylenebutenolidase homolog (Pseudomonas)","description":"CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]","ncbiEntrezGeneId":134147,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/134147","proteins":[{"symbol":"CMBL_HUMAN","href":"/api/1.0/protein/CMBL_HUMAN"}],"hgncRootFamilies":[]}